Study enhances specificity of microglial genetic targeting in mice, indicating improved precision in manipulation.
mice and eliminated confounding contributions from peripheral macrophages. In sum, the use of a CSF1R inhibitor provides a solution to enhance the precision of microglial genetic manipulation using a common Cre line.
No takes yet. Share an insight, caveat, or question.
Babcock et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: