Key points are not available for this paper at this time.
Abstract Sulfondiimines are diaza‐analogues of sulfones with a chiral sulfur center. Compared to sulfones and sulfoximines, their synthesis and transformations have so far been studied to a lesser extent. Here, we report the enantioselective synthesis of 1,2‐benzothiazine 1‐imines, i.e., cyclic sulfondiimine derivatives from sulfondiimines and sulfoxonium ylides via C−H alkylation/cyclization reactions. The combination of Ru( p ‐cymene)Cl 2 2 and a newly developed chiral spiro carboxylic acid is key to achieving high enantioselectivity.
Huang et al. (Wed,) studied this question.