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January 1, 2025ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)Open Access

Peritumoral Budding as a Predictor for Lymph Node Metastases in Colorectal Carcinomas: What Is the Importance?

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Authors

ESEmily Karoline Araujo Nonato Dos SantosFaculdade Evangélica do ParanáBTBruna Gama TrichesFaculdade Evangélica do ParanáGSGuilherme Prestes da SilvaFaculdade Evangélica do Paraná

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Implication

Cross-sectional study assesses tumor budding's role in predicting lymph node metastases in colorectal cancer, indicating its relevance in prognosis.

Key Points

  • This study aims to determine the predictive power of tumor budding for lymph node metastases in colorectal cancer.
  • Cross-sectional, retrospective study reviewing medical records and histopathological reports.
  • Examined records of 153 patients who underwent oncologic surgery for colorectal cancer.
  • Analyzed associations between tumor budding and lymph node metastases.
  • 63.39% of patients exhibited tumor budding; 51.55% had a high budding score.
  • Statistically significant association between tumor budding and lymph node metastasis (p<0.05).
  • Regional lymph node metastases found in 66 patients, indicating high relevance for prognosis.

Cite This Study

Santos et al. (2025) studied this question.

synapsesocial.com/papers/6a1e597f60864841a668ca0chttps://doi.org/10.1590/0102-6720202500006e1875
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tumour budding: a promising parameter in colorectal cancer2012 · 213 citations
  2. 2COLORECTAL CANCER: ASSOCIATION BETWEEN SOCIODEMOGRAPHIC VARIABLES AND THE ADHERENCE TO CANCER SCREENING2023 · 10 citations
  3. 3Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries2021 · 114,920 citations