Why the study?
Does baseline ventriculo-arterial coupling predict stroke volume response to norepinephrine infusion in hypotensive postoperative cardiac surgery patients?
Population
28 postoperative cardiac surgery patients with persistent arterial hypotension in the immediate postcardiac…
Comparison
Norepinephrine infusion vs Baseline (before norepinephrine infusion)
Design
Cohort
Follow-up
immediate postcardiac surgery period
Authors
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Baseline Ea/Ees ratio may identify norepinephrine responders; hypothesis-generating and requires prospective validation before clinical use.
Does baseline ventriculo-arterial coupling predict stroke volume response to norepinephrine infusion in hypotensive postoperative cardiac surgery patients?
In hypotensive postoperative cardiac surgery patients, norepinephrine increases stroke volume only in those with altered baseline ventriculo-arterial coupling, which can be predicted by the arterial elastance to end-systolic ventricular elastance ratio.
Guinot et al. (2017) studied this question.
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