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September 17, 2008Proceedings of the National Academy of SciencesOpen Access

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

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HDHansong DengShanghai Sunshine Rehabilitation CenterMDMark DodsonIntermountain Medical CenterHHHaixia HuangTsinghua University

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Deng et al. (2008) studied this question.

synapsesocial.com/papers/6a1e5f09a42c1ff064328872https://doi.org/10.1073/pnas.0803998105
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Environment, Mitochondria, and Parkinson's Disease2002 · 229 citations
  2. 2PINK1 protein in normal human brain and Parkinson's disease2006 · 337 citations
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  4. 4Fzo1p Is a Mitochondrial Outer Membrane Protein Essential for the Biogenesis of Functional Mitochondria in Saccharomyces cerevisiae1998 · 371 citations
  5. 5Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin2007 · 515 citations