Why the study?
Does blood flow restriction during low-intensity aerobic exercise trigger hypoalgesia and activate opioid and endocannabinoid systems?
Does blood flow restriction during low-intensity aerobic exercise trigger hypoalgesia and activate opioid and endocannabinoid systems?
Blood flow restriction during low-intensity aerobic exercise induces hypoalgesia through the activation of opioid and endocannabinoid systems, offering a potential alternative to high-intensity exercise for pain modulation.
May offer low-intensity BFR exercise as hypoalgesic alternative; leaves open clinical translation and durability in patients.
We have shown that performing blood flow restriction (BFR) during low-intensity aerobic exercise can trigger local and systemic hypoalgesia, which is not typically observed with this intensity of exercise. High-pressure BFR triggers greater and comparable hypoalgesia than high-intensity aerobic exercise in the exercising limbs and remote areas of the body, respectively. Performing BFR during low-intensity aerobic exercise activates the opioid and endocannabinoid systems, providing novel insight into potential mechanisms of hypoalgesia with BFR exercise
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Hughes et al. (2021) studied this question.
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