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This research aims to investigate how exercise induces changes in the endocannabinoid system related to analgesia and sedation.

November 20, 2003NeuroreportOpen Access

Exercise activates the endocannabinoid system

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This research aims to investigate how exercise induces changes in the endocannabinoid system related to analgesia and sedation.
Trained male college students performed 50 minutes of exercise on a treadmill or stationary bike at 70-80% max heart rate.
Neurochemical changes related to the endocannabinoid system were measured during and after exercise.
Exercise of moderate intensity activates the endocannabinoid system.
This activation suggests a possible mechanism for exercise-induced analgesia.
Evidence points toward potential psychological and physiological adaptations from exercise.

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Randomized trial shows exercise activates the endocannabinoid system in male students, suggesting a new mechanism for analgesia.

Sparling et al. (2003) studied this question.

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