IntelliProfiler 2.0: An integrated R pipeline for long-term home-cage behavioral profiling in group-housed mice using eeeHive 2D

Q: What does this research mean for the field?

IntelliProfiler 2.0 is a fully R-based pipeline that provides a reproducible and extensible framework for analyzing high-density RFID tracking data to quantify long-term behavioral profiles in group-housed mice. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Shohei Ochi; Masashi Azuma; Iori hara; Hitoshi Inada; Kento Takabayashi; Noriko Osumi

doi:10.1016/j.jneumeth.2026.110816

May 1, 2026Journal of Neuroscience MethodsOpen Access

IntelliProfiler 2.0: An integrated R pipeline for long-term home-cage behavioral profiling in group-housed mice using eeeHive 2D

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Key Points

The aim is to develop an R-based pipeline, IntelliProfiler 2.0, for better analysis of long-term home-cage behaviors in group-housed mice.
Developed an R-based pipeline for behavioral analysis using eeeHive 2D RFID technology.
Conducted four-day recordings of group-housed C57BL/6J mice (8 males and 8 females) to analyze data.
Implemented features for statistical testing, preprocessing, and data visualization within the same framework.
IntelliProfiler 2.0 captured circadian phase-dependent locomotion patterns and sex-dependent differences.
Radar-chart summaries allowed for intuitive comparisons of behavioral profiles across light/dark cycles.
The new pipeline improved reproducibility and reduced operational complexity compared to prior versions.

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Implication

Demonstrates an R pipeline improves behavioral profiling accuracy in group-housed mice, highlighting reproducibility and analytic validity.

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Ochi et al. (2026) studied this question.

synapsesocial.com/papers/6a1e720230b38c64201b558d https://doi.org/10.1016/j.jneumeth.2026.110816

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IntelliProfiler 2.0: An integrated R pipeline for long-term home-cage behavioral profiling in group-housed mice using eeeHive 2D

Key Points

No abstract yet

Implication

Discussion

Cite This Study

IntelliProfiler 2.0: An integrated R pipeline for long-term home-cage behavioral profiling in group-housed mice using eeeHive 2D

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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