Self-Rated Health and Embryo Transfer Outcomes in Women with Infertility: Evidence from a Prospective Cohort Study

OBJECTIVE: To study the association between self-rated health and in vitro fertilization outcomes in women with infertility undergoing embryo transfer. DESIGN: Prospective cohort study. SUBJECTS: A total of 800 women with infertility undergoing embryo transfer at a tertiary reproductive center in China. EXPOSURE: Self-rated health assessed across physical, psychological, social, and overall domains on the day of embryo transfer. MAIN OUTCOME MEASURES: Clinical pregnancy, implantation rate, biochemical pregnancy, and early miscarriage. RESULTS: Self-rated health in any domain was not significantly associated with clinical pregnancy, implantation rate, biochemical pregnancy, or early miscarriage after adjustment for demographic and clinical confounders. CONCLUSION: Self-rated health was not associated with in vitro fertilization outcomes, suggesting that treatment prognosis is primarily driven by biological and clinical factors.