Towards An Artificial Cornea: Surface Modifications of Optically Clear, Oxygen Permeable Soft Contact Lens Materials by Ammonia Plasma Modification Technique for the Enhanced Attachment and Growth of Corneal Epithelial Cells

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The advent of high water content, oxygen permeable contact lens materials has made the intracorneal implants more feasible. A major obstacle encountered is the regrowth of a stable epithelium over the implant. Therefore, ammonia gaseous plasma modification technique was used to modify the surface chemical properties of soft contact lens material such as poly(2-hydroxyethyl methacrylate and methacrylic acid), PHEMA-MAA copolymer, in an attempt to enhance the cell attachment and growth of rabbit corneal epithelial cells.