Why the study?
Does TNF-alpha inhibit insulin-stimulated glucose uptake and endothelium-dependent vasodilation in healthy lean male volunteers?
Does TNF-alpha inhibit insulin-stimulated glucose uptake and endothelium-dependent vasodilation in healthy lean male volunteers?
TNF-alpha acutely inhibits insulin-stimulated glucose uptake and endothelium-dependent vasodilation in humans, supporting a role for inflammation in insulin resistance and vascular dysfunction.
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TNF-α impairs insulin action and endothelial function in humans; hypothesis-generating for inflammation in insulin resistance, requiring clinical validation.
Rask‐Madsen et al. (2003) studied this question.
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