Population
Passive cardiac tissue (uniaxial papillary muscle and biaxial experimental data)
Design
Preclinical
Authors
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Models using uniaxial parameters may underestimate multiaxial myocardial stresses; leaves open validated transversely-isotropic constitutive laws for cardiac biomechanics.
A proposed pseudostrain-energy function demonstrates that multiaxially-loaded cardiac tissue behaves as nearly transversely-isotropic, highlighting the inadequacy of uniaxial data for predicting multiaxial stresses.
Humphrey et al. (1987) studied this question.
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