This review summarizes the clinical characteristics, genetics, and diagnostic and therapeutic strategies for catecholaminergic polymorphic ventricular tachycardia (CPVT).
Offers clinicians a CPVT management reference; extends prior syntheses but leaves open needs for prospective therapeutic trials.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia disorder that is characterized by emotion- and exercise-induced polymorphic ventricular arrhythmias and may lead to sudden cardiac death (SCD). CPVT plays an important role in SCD in the young and therefore recognition and adequate treatment of the disease are of vital importance. In the past years tremendous improvements have been made in the diagnostic methods and treatment of the disease. In this review, we summarize the clinical characteristics, genetics, and diagnostic and therapeutic strategies of CPVT and describe the most recent advances and some of the current challenges. (Circ J 2016; 80: 1285-1291).
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Lieve et al. (2016) studied this question.