Hypothyroidism can cause isolated atrial pacemaker lead dysfunction, which may be reversible with thyroid hormone replacement.
Hypothesis-generating for reversible atrial lead dysfunction in hypothyroidism; larger studies needed before clinical consideration.
Hypothyroidism is known to have a multitude of cardiac electrophysiologic effects, including bradycardia, atrioventricular block, prolonged QT interval, and elevated ventricular pacing thresholds. We report the case of a 36-year-old woman who presented with isolated dysfunction of her atrial pacemaker lead, which reversed with thyroid hormone replacement.
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Patton et al. (2008) studied this question.
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