Why the study?
Patients with malignant neoplasms have an increased risk of cerebrovascular complications, prompting a review of the role of cisplatin and radiation therapy.
Cerebrovascular complications in cancer patients, potentially influenced by treatments like cisplatin and radiation therapy, require a multidisciplinary approach for proper management and prognostication.
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May warrant cerebrovascular monitoring in cancer patients on cisplatin or radiation; leaves open prospective studies to quantify risks.
Patients with malignant neoplasms have an increased risk of cerebrovascular complications (intratumoral hemorrhage, invasion of arterial and venous sinus by tumor mass or leptomeningeal infiltrates, and tumor embolism). The review discusses the role and importance of cisplatin and radiation therapy in the occurrence of cerebrovascular complications in patients with malignant neoplasms that may occur before, during or years after treatment. Descriptions of individual clinical observations of the lesions of the central nervous system in the treatment of cancer are provided. The type and mechanism of stroke, as well as the stage and pathology of the neoplasm, dictate the use of a multidisciplinary approach, which ensures proper management and helps to outline the prognosis in this category of patients.
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Муркамилов et al. (2021) studied this question.
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