August 1, 1985PEDIATRICS
Cerebrovascular Accidents in Children with Cancer
Key result
Cerebrovascular accidents in children with cancer are relatively frequent and often related to disseminated intravascular coagulation, specific chemotherapies, or metastatic tumors.
Why the study?
What are the causes and clinical syndromes of cerebrovascular accidents in children with cancer?
Population
26 children with systemic malignancies who suffered cerebrovascular accidents over a 4-year period
Design
Case_series
Authors
Discussion
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Implication
Awareness of CVA risk in pediatric malignancy is warranted; leaves open optimal prevention strategies.
Study Design
Type
Observational (n=26)
Structured PICO
What are the causes and clinical syndromes of cerebrovascular accidents in children with cancer?
P
Population
26 children with systemic malignancies who suffered cerebrovascular accidents over a 4-year period.
O
Outcome
Causes and clinical syndromes of cerebrovascular accidentshard clinical
Cerebrovascular accidents in children with cancer are frequently caused by specific syndromes including DIC-associated thrombosis, chemotherapy toxicity (L-asparaginase, methotrexate), and metastatic disease.
Cite This Study
Packer et al. (1985) conducted an observational in Systemic malignancies (n=26). Systemic malignancies and cancer treatments was evaluated on Causes and associations of cerebrovascular accidents. Cerebrovascular accidents in children with cancer are relatively frequent and often related to disseminated intravascular coagulation, specific chemotherapies, or metastatic tumors.