Key result
Comorbidities affect ~31% of hypertensive patients, linked to older age, longer duration, alcohol, and inactivity.
Why the study?
Hypertension frequently coexists with chronic conditions like diabetes, dyslipidemia, chronic kidney disease, and obesity, prompting an assessment of comorbidity prevalence and associated factors.
Cross-Sectional (n=423)
Yes
Nearly one-third of hypertensive patients in Northwest Ethiopia have at least one comorbidity, underscoring the need for integrated care and targeted interventions addressing modifiable risk factors.
Hypertension frequently coexists with chronic conditions such as diabetes, dyslipidemia, chronic kidney disease, and obesity. This study aimed to assess the prevalence and associated factors of comorbidities among hypertensive patients in northwest Ethiopia. A multi-centered, institution-based cross-sectional study was conducted in 2024 among 423 randomly selected hypertensive patients. Data was collected through structured interviews and physical assessments. Bivariate and multivariate logistic regression analyses were employed to identify significant associations, with p-values < 0.05 considered statistically significant. The prevalence of comorbidities among hypertensive patients was 30.5% (95% CI: 26.2–34.8%). The most common comorbidities were chronic kidney disease (10.9%), diabetes mellitus (9%), dyslipidemia (7.5%), and obesity (3.1%). Factors significantly associated with comorbidity included age ≥ 65 years (AOR = 1.77), hypertension duration ≥ 5 years (AOR = 1.99), alcohol consumption (AOR = 1.93), and physical inactivity (AOR = 1.9). Nearly one-third of hypertensive patients had at least one comorbid condition. The findings underscore the importance of early detection, integrated care, and targeted interventions, which are supported by enhanced diagnostic services, health worker training, and public awareness. Further longitudinal and community-based studies are recommended to explore causality and broader impacts.
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Ashenef et al. (2025) conducted a cross-sectional in Hypertension (n=423). Risk factors (age ≥ 65, hypertension duration ≥ 5 years, alcohol consumption, physical inactivity) vs. Absence of risk factors was evaluated on Prevalence of comorbidities (30.5%, 95% CI 26.2-34.8). The overall prevalence of comorbidities among hypertensive patients was 30.5%, with age ≥ 65 years, hypertension duration ≥ 5 years, alcohol consumption, and physical inactivity identified as significant risk factors.
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