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PURPOSE: was developed to embed and extract even the smallest fragments with conventional baskets. This study aimed to evaluate the safety and feasibility-defined as the ability to extract fragments 18 years with kidney stones > 8 mm and no anatomical abnormalities. Patients were randomized to flexible ureterorenoscopy + hydrogel (Group 1) or flexible ureterorenoscopy (Group 2) alone. After laser lithotripsy, fragments were retrieved either embedded in hydrogel or individually, and categorized by size ( 1.0 mm). Explorative statistical analyses included Mann-Whitney U, Student's t-test, and Chi-square test. Adverse events were monitored intraoperatively and during a 6-week follow-up. RESULTS: Of 65 screened patients, 40 were analysed (Group 1: n = 23; Group 2: n = 17). The hydrogel method significantly retrieved more fragments 1 mm (310 vs. 118). On a per-patient level, more < 1 mm fragments were removed in Group 1 (median 7 IQR 21 vs. 0 2, p < 0.003). Surgery duration was longer in Group 1 (80 28 vs. 62 20 minutes, p = 0.02). No serious adverse events were reported. CONCLUSIONS: The hydrogel method was a safe and feasible addition to fURS, allowing improved retrieval of even the smallest fragments without added risk. The main limitations are the small sample size and absence of long-term stone-free and recurrence data, underscoring the need for larger confirmatory studies.
Amiel et al. (Fri,) studied this question.