What question did this study set out to answer?

To summarize recent progress in the synthesis, supramolecular self-assembly, and multifunctional theranostic applications of boron dipyrromethene (BODIPY) fluorophores in biomedicine.

November 18, 2022Advanced Materials

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

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Authors

HCHong‐Bo ChengBeijing University of Chemical Technology XCXiaoqiao CaoZhanjiang Experimental Station SZShuchun ZhangLiaoning Normal University

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Implication

Review highlights advances in BODIPY self-assembly and theranostic applications across imaging and therapy, indicating substantial potential for multifunctional nanomedicine.

Key Points

To summarize recent progress in the synthesis, supramolecular self-assembly, and multifunctional theranostic applications of boron dipyrromethene (BODIPY) fluorophores in biomedicine.
Reviewed synthetic routes, regulatory mechanisms, and post-functionalization chemical strategies for BODIPY derivatives.
Evaluated single- and multicomponent supramolecular self-assembly frameworks forming aqueous nanostructures.
Surveyed diagnostic and therapeutic applications alongside translational challenges facing biomedical translation.
BODIPY-based supramolecular architectures reliably enable dual-mode diagnostic performance through fluorescence bioimaging and photoacoustic imaging.
Engineered BODIPY assemblies provide effective multimodal intervention platforms, integrating photodynamic therapy, photothermal therapy, and immunotherapy.
Identified critical design requirements to overcome biocompatibility and solubility challenges for future clinical development.

Cite This Study

Cheng et al. (2022) studied this question.

synapsesocial.com/papers/6a1eafaa6540130b7faf2e3c https://doi.org/10.1002/adma.202207546

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Implication

Review highlights advances in BODIPY self-assembly and theranostic applications across imaging and therapy, indicating substantial potential for multifunctional nanomedicine.

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

Discussion

Member takes

Implication

Key Points

Cite This Study

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

Discussion

Member takes

Implication

Key Points

Cite This Study

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