Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 1, 1997Pacing and Clinical Electrophysiology

A Comparison of Transvenous Atrial Defibrillation of Acute and Chronic Atrial Fibrillation and the Effect of Intravenous Sotalol on Human Atrial Defibrillation Threshold

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does intravenous sotalol reduce the atrial defibrillation threshold during transvenous atrial defibrillation in patients with acute and chronic atrial fibrillation?

Population

38 patients, comprising 25 with chronic atrial fibrillation and 13 with acute atrial fibrillation.

Comparison

Transvenous atrial defibrillation followed by… vs Acute vs. chronic atrial fibrillation groups…

Design

Cohort

Authors

CLChu‐Pak LauUniversity of Hong KongNLNgai-Sang LokQueen Mary Hospital

Discussion

Loading...

Member takes

Implication

Sotalol may lower energy needs for acute AF cardioversion but not chronic; hypothesis-generating and requires randomized confirmation before practice consideration.

Structured PICO

Does intravenous sotalol reduce the atrial defibrillation threshold during transvenous atrial defibrillation in patients with acute and chronic atrial fibrillation?

P
Population
38 patients, comprising 25 with chronic atrial fibrillation and 13 with acute atrial fibrillation.
I
Intervention
Transvenous atrial defibrillation (R wave synchronized, biphasic shocks between the right atrium and coronary sinus) followed by intravenous sotalol 1.5 mg/kg given over 15 minutes.
C
Comparator
Acute vs. chronic atrial fibrillation groups; baseline vs. post-sotalol administration.
O
Outcome
Atrial defibrillation threshold (ADFT), defined as the lowest energy and voltage resulting in successful defibrillation.surrogate

Cite This Study

Lau et al. (1997) studied this question.

synapsesocial.com/papers/6a1eb841989adebfe89a7ff2https://doi.org/10.1111/j.1540-8159.1997.tb06084.x

Topics

Persistent AF managementAtrial fibrillationAnticoagulation in AFAF ablation outcomes
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Internal transvenous low energy cardioversion for the treatment of cardiac arrhythmias.1984 · 77 citations
  2. 2New Method for Terminating Cardiac Arrhythmias1986 · 578 citations
  3. 3Internal cardioversion of atrial fibrillation in sheep.1993 · 194 citations