Key result
Isolated OSA events linked to ~15% surge in SBP, varying across sleep stages.
Why the study?
Wide variability in trajectories of nocturnal blood pressure surges challenges the quantification, characterization, and mathematical modeling of blood pressure surge dynamics in obstructive sleep apnea.
Do isolated obstructive sleep apnea events increase nocturnal blood pressure surges in patients with moderate to severe OSA?
Observational (n=10)
Single-blind (scorer blinded to objectives)
No
Do isolated obstructive sleep apnea events increase nocturnal blood pressure surges in patients with moderate to severe OSA?
Effect estimate: 19 ± 7.1 mmHg (14.8%) increase in SBP and 11 ± 5.6 mmHg (15.5%) increase in DBP
This study provides a granular method for quantifying apnea-induced blood pressure surges, demonstrating significant BP oscillations that vary by sleep stage.
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Isolated OSA events may drive nocturnal BP instability; hypothesis-generating for stage-specific monitoring in larger cohorts.
Chaung et al. (2023) conducted an observational in Obstructive sleep apnea (n=10). Isolated obstructive sleep apnea events vs. Baseline blood pressure during normal breathing/wakefulness was evaluated on Surges in systolic and diastolic blood pressure (19 ± 7.1 mmHg (14.8%) increase in SBP and 11 ± 5.6 mmHg (15.5%) increase in DBP). Isolated obstructive sleep apnea events increased systolic and diastolic blood pressure by 19 ± 7.1 mmHg and 11 ± 5.6 mmHg, respectively, with amplitudes varying across sleep stages.
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