Key result
Holding oral anticoagulation fails to reduce hospital stay vs continuing therapy in atraumatic haemarthrosis.
Why the study?
The study was conducted to investigate the management and outcomes of different management strategies in patients admitted to the hospital with acute haemarthrosis while taking oral anticoagulants.
Does holding oral anticoagulation reduce length of hospital stay in patients admitted with atraumatic haemarthrosis?
Cohort (n=31)
No
Does holding oral anticoagulation reduce length of hospital stay in patients admitted with atraumatic haemarthrosis?
Absolute Event Rate: 4.2% vs 13.1%
p-value: p=0.124
Holding oral anticoagulation in patients with atraumatic haemarthrosis does not significantly alter length of hospital stay, suggesting individualized management is reasonable.
No difference in length of stay supports individualized decisions; leaves open optimal periprocedural strategy pending prospective trials.
Aims: Our aim was to investigate the management of patients who were admitted to hospital with an acute haemarthrosis whilst taking oral anticoagulants, and highlight the outcomes of different management strategies. Methods: A retrospective review was performed of all orthopaedic admissions over a 42-month period (January 2015-July 2018) to the Orthopaedic Department of a London District General Hospital. All patients admitted with a spontaneous joint haemarthrosis and concomitant use of oral anticoagulants was identified. Anonymised data was placed on a secure trust database. Findings: A total of 31 patients were included. 22 patients (71%) had their anticoagulant temporarily held during admission. 9 patients (32%) had their anticoagulation reversed with 10 mg of vitamin K. 5 patients had their haemarthrosis aspirated either on admission or during their hospital stay. The overall mean length of stay in patients with a haemarthrosis was 7.0 days. The mean length of stay in patients who had their anticoagulation held was 8.6 days. In contrast, patients who continued taking their anticoagulation were found to have an average length of stay of 2.3 days. No patients suffered a thrombotic event in the 60 days following discharge. No adverse events were recorded following joint aspiration. Conclusion: There is currently no consensus on the management of haemarthrosis in patients on oral anticoagulants. Continuing the anticoagulants did not increase length of hospital stay. Further research may focus on assessing the effect of management adjuncts on patient outcomes and their cost effectiveness to aid the development of local and/or national guidelines.
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Dalrymple et al. (2022) conducted a cohort in Atraumatic knee joint haemarthrosis on oral anticoagulants (n=31). Holding oral anticoagulation vs. Continuing oral anticoagulation was evaluated on Length of hospital stay (p=0.124). Holding oral anticoagulation during admission for atraumatic haemarthrosis did not significantly affect the length of hospital stay compared to continuing anticoagulation (4.2 vs 13.1 days, p=0.124).
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