Key result
Pre-admission use of oral anticoagulants in patients with hip fractures did not significantly affect hospital mortality (6.5% vs 6.79%) or postoperative outcomes after adjusting for patient characteristics.
Why the study?
The management of hip fracture patients is affected by oral anticoagulants, but differences in health outcomes compared to non-anticoagulated patients needed investigation.
Do oral anticoagulants affect health outcomes and time to surgery in patients aged 50 years and over presenting with hip fractures?
Population
2307 patients aged 50 years and over presenting with hip fractures to a large university hospital
Comparison
Anticoagulated vs not anticoagulated
Design
Registry-based cross-sectional analysis
Authors
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Reassures on pre-admission oral anticoagulant use in hip fractures; observational data leaves randomized confirmation open.
Cross-Sectional (n=2,307)
No
Do oral anticoagulants affect health outcomes and time to surgery in patients aged 50 years and over presenting with hip fractures?
Absolute Event Rate: 6.5% vs 6.79%
p-value: p=0.88
Patients on oral anticoagulants presenting with hip fractures do not experience significantly worse health outcomes or clinically meaningful surgical delays compared to non-anticoagulated patients after adjusting for baseline comorbidities.
Hoerlyck et al. (2019) conducted a cross-sectional in Hip fracture (n=2,307). Oral anticoagulants (warfarin and DOACs) vs. Not anticoagulated was evaluated on Hospital mortality (p=0.88). Pre-admission use of oral anticoagulants in patients with hip fractures did not significantly affect hospital mortality (6.5% vs 6.79%) or postoperative outcomes after adjusting for patient characteristics.
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