January 2, 1968Acta Physiologica Scandinavica

The Mechanical Parameters of Myocardial Contraction Studied at a Constant Length of the Contractile Element

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Population

Isolated papillary muscles of the rabbit

Design

Preclinical

Authors

KEK. A. P. EdmanAstraZeneca (Sweden)ENErik NilssonLund University

Discussion

Member takes

Implication

Should not alter clinical assessment of myocardial contractility; leaves open active-state determinants in intact human hearts.

Structured PICO

Population

Isolated papillary muscles of the rabbit

Intervention

Measurement of mechanical parameters (time course of the active state, force-velocity relation, and series compliance) at a constant length of the contractile element

Outcome

Mechanical parameters of myocardial contraction including force-velocity curve, active state time course, and series elastic element stiffness

This preclinical study demonstrates that the duration of the active state in myocardial contraction is determined by the amount of shortening of the contractile element, and that force-producing structures do not substantially contribute to series compliance.

Cite This Study

Edman et al. (1968) studied this question.

synapsesocial.com/papers/6a1ebc936b4935698da443cc https://doi.org/10.1111/j.1365-201x.1968.tb10828.x

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The Mechanical Parameters of Myocardial Contraction Studied at a Constant Length of the Contractile Element

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Mechanical Parameters of Myocardial Contraction Studied at a Constant Length of the Contractile Element

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider