What does this research mean for the field?

The PreOperative Score to predict PostOperative Mortality (POSPOM), based on 17 preoperative factors, accurately predicts in-hospital mortality in surgical patients with excellent discrimination. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To develop and validate a simple surgical risk score using solely preoperative variables to accurately predict in-hospital mortality.

December 11, 2015Anesthesiology

Preoperative Score to Predict Postoperative Mortality (POSPOM)

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Why the study?

Does the PreOperative Score to predict PostOperative Mortality (POSPOM) accurately predict in-hospital mortality in adult surgical patients?

Key Points

To develop and validate a simple surgical risk score using solely preoperative variables to accurately predict in-hospital mortality.
Extracted 2010 nationwide hospital data from France on adult surgical patients undergoing procedures requiring anesthesia (N=5,507,834).
Evaluated 29 preoperative factors (age, ICD-10 comorbidities, surgery type) across a derivation cohort (N=2,717,902) and validated the resulting score in an independent cohort (N=2,789,932).
In-hospital mortality occurred in 0.47% of patients (12,786 deaths; 95% CI, 0.46% to 0.48%) in the derivation cohort and 0.54% (14,933 deaths; 95% CI, 0.53% to 0.55%) in the validation cohort.
The final 17-predictor POSPOM score demonstrated excellent discrimination for in-hospital mortality, with a c-statistic of 0.944 (95% CI, 0.943 to 0.945) in the development cohort and 0.929 (95% CI, 0.928 to 0.931) in the validation cohort.

Structured PICO

Does the PreOperative Score to predict PostOperative Mortality (POSPOM) accurately predict in-hospital mortality in adult surgical patients?

Population

5,507,834 patients aged 18 years or older undergoing surgeries requiring anesthesia in France.

Intervention

PreOperative Score to predict PostOperative Mortality (POSPOM) based on 17 preoperative factors

Outcome

In-hospital mortalityhard clinical

The POSPOM score provides a highly discriminative, simple tool based solely on preoperative factors to predict in-hospital mortality in surgical patients.

Discussion

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Implication

Supports preoperative mortality risk stratification with POSPOM; leaves open prospective validation of clinical utility.

Cite This Study

Manach et al. (2015) studied this question.

synapsesocial.com/papers/6a1ebdaa99b676b6b9af3cff https://doi.org/10.1097/aln.0000000000000972

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Preoperative Score to Predict Postoperative Mortality (POSPOM)

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Preoperative Score to Predict Postoperative Mortality (POSPOM)

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider