The methanol extract of Cassia fistula was investigated for its effect on a cough model induced by sulphur dioxide gas in mice. It exhibited significant antitussive activity when compared with control in a dose dependent manner. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototypes antitussive agent. The C. fistula extract (400, 600 mg/kg, p.o.) showed maximum inhibition of cough by 44.44% and 51.85% with respect to control group.
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Bhakta et al. (1998) studied this question.
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