Key result
This review summarizes literature on biomarkers of acute myocardial damage, such as troponins and CPK, and their correlation with the degree of damage caused by radiofrequency ablation.
Why the study?
What are the markers of acute myocardial damage after radiofrequency ablation of tachyarrhythmia?
What are the markers of acute myocardial damage after radiofrequency ablation of tachyarrhythmia?
This review summarizes current knowledge on various biomarkers used to assess acute myocardial damage following radiofrequency ablation for tachyarrhythmia.
May support troponin/CPK monitoring post-RFA; leaves open prospective validation of damage correlation.
This study presents literature data over the past few years on markers of acute myocardial damage after radiofrequency ablation. Information on markers such as troponin I and T, creatine phosphokinase and its fractions, CRP and interleukins and myoglobin is presented in detail. For each potential myocardial damage indicator, data related to their expression site, chemical basis of each marker and correlation between the degree of damage caused by radiofrequency exposure and the levels of various biomarkers of myocardial damage are provided.Received 12 November 2019. Revised 26 February 2020. Accepted 27 February 2020.Funding: The study did not have sponsorship.Conflict of interest: Authors declare no conflict of interest.Author contributionsConception and study design: O.L. Zajfrid, R.B. Tatarsky, E.S. VasichkinaDrafting the article: O.L. Zajfrid, K.A. Chueva, A.V. Mikhailov Critical revision of the article: O.L. Zajfrid, R.B. Tatarsky, E.S. Vasichkina, I.L. Nikitina, D.S. LebedevFinal approval of the version to be published: O.L. Zajfrid, K.A. Chueva, E.S. Vasichkina, A.V. Mikhailov, D.S. Lebedev, I.L. Nikitina, R.B. Tatarsky
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Zayfrid et al. (2020) conducted a review in Tachyarrhythmia undergoing radiofrequency ablation. Radiofrequency ablation was evaluated on Markers of acute myocardial damage. This review summarizes literature on biomarkers of acute myocardial damage, such as troponins and CPK, and their correlation with the degree of damage caused by radiofrequency ablation.
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