Low brachial-ankle pulse wave velocity (<1314 cm/s) was independently associated with normal left ventricular diastolic function (OR 2.58; 95% CI 1.46-4.57; P=0.001).
Observational (n=267)
Is low arterial stiffness associated with preserved left ventricular diastolic function in middle-aged and elderly patients without cardiovascular disease?
Reduced arterial stiffness is independently associated with preserved left ventricular diastolic function in middle-aged and older adults without known cardiovascular disease.
Odds Ratio: 2.58 (95% CI 1.46–4.57)
p-value: p=0.001
The aim of this study was to investigate whether arterial stiffness plays a role in retaining normal diastolic function in a middle‐aged and elderly Korean population. A total of 267 patients without documented cardiovascular disease, 50 years and older (mean age, 57.3±6.3 years; 69.8% men) were retrospectively analyzed. All patients underwent both transthoracic echocardiography and brachial‐ankle pulse wave velocity measurement on the same day. Patients with septal annular peak velocity (e’) ≥8 cm/s and left atrial volume index <34 mL /m 2 were considered as having normal diastolic function. Ninety‐eight patients (36.7%) had normal diastolic function. Low brachial‐ankle pulse wave velocity (<1314 cm/s) was an independent factor for determining normal diastolic function even after controlling for potential confounders in multiple logistic regression analysis (odds ratio, 2.58; 95% confidence interval, 1.46–4.57; P =.001). Our results suggest that compliant arteries may play an important role in maintaining normal left ventricular diastolic function in middle‐aged and elderly patients without documented cardiovascular disease.
Park et al. (2017) conducted an observational in Without documented cardiovascular disease (n=267). Low brachial-ankle pulse wave velocity (<1314 cm/s) vs. Higher brachial-ankle pulse wave velocity was evaluated on Normal diastolic function (OR 2.58, 95% CI 1.46-4.57, p=0.001). Low brachial-ankle pulse wave velocity (<1314 cm/s) was independently associated with normal left ventricular diastolic function (OR 2.58; 95% CI 1.46-4.57; P=0.001).