Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 5, 2009BloodOpen Access

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities

View Full Paper
Ask AI
Bookmark
Share

Authors

AMAnja MottokUniversität UlmCRChristoph RennéDeutsche Klinik für DiagnostikMSMarc SeifertDüsseldorf University Hospital

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Mottok et al. (2009) studied this question.

synapsesocial.com/papers/6a1ec41fbf2a5d44faaf4b11https://doi.org/10.1182/blood-2009-06-225839
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Somatic hypermutation of SOCS1 in lymphocyte-predominant Hodgkin lymphoma is accompanied by high JAK2 expression and activation of STAT62007 · 142 citations
  2. 2Somatic hypermutation in normal and transformed human B cells1998 · 341 citations
  3. 3Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line2004 · 215 citations
  4. 4Aberrant somatic hypermutation in post‐transplant lymphoproliferative disorders2004 · 31 citations
  5. 5Aberrant somatic hypermutation in tumor cells of nodular-lymphocyte-predominant and classic Hodgkin lymphoma2006 · 87 citations