Key result
Acetylstrophanthidin increased myocardial oxygen consumption at a constant load, an augmentation related to the change in the contractile state of the muscle.
Population
19 cat papillary muscles
Comparison
Acetylstrophanthidin vs Baseline/control conditions prior to…
Design
Preclinical
Authors
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Caution with inotropes in ischemia; leaves open human translation from animal models.
Acetylstrophanthidin augments myocardial oxygen consumption by increasing the contractile state (velocity of contraction) of the cardiac muscle.
Henry Neal Coleman (1967) studied this question. Acetylstrophanthidin vs. Baseline/control conditions was evaluated on Myocardial oxygen consumption (MVO2). Acetylstrophanthidin increased myocardial oxygen consumption at a constant load, an augmentation related to the change in the contractile state of the muscle.
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