Key result
Pain induction via the Cold Pressor Task significantly increased heart rate, sudomotor activity, and muscle contraction force, while decreasing parasympathetic influence compared to non-painful periods.
Why the study?
Pain intensity assessment still relies on self-reports, but autonomic nervous system reactivity may provide an objective method to assess pain.
Does pain induction alter physiological signals (ECG, EMG, EDA) compared to non-painful periods?
Observational (n=45)
No
Does pain induction alter physiological signals (ECG, EMG, EDA) compared to non-painful periods?
Pain induction elicits measurable physiological changes in autonomic nervous system activity, including increased heart rate, sympathetic EDA activity, and decreased parasympathetic HRV influence.
Pain is a complex phenomenon that arises from the interaction of multiple neuroanatomic and neurochemical systems with several cognitive and affective processes. Nowadays, the assessment of pain intensity still relies on the use of self-reports. However, recent research has shown a connection between the perception of pain and exacerbated stress response in the Autonomic Nervous System. As a result, there has been an increasing analysis of the use of autonomic reactivity with the objective to assess pain. In the present study, the methods include pre-processing, feature extraction, and feature analysis. For the purpose of understanding and characterizing physiological responses of pain, different physiological signals were, simultaneously, recorded while a pain-inducing protocol was performed. The obtained results, for the electrocardiogram (ECG), showed a statistically significant increase in the heart rate, during the painful period compared to non-painful periods. Additionally, heart rate variability features demonstrated a decrease in the Parasympathetic Nervous System influence. The features from the electromyogram (EMG) showed an increase in power and contraction force of the muscle during the pain induction task. Lastly, the electrodermal activity (EDA) showed an adjustment of the sudomotor activity, implying an increase in the Sympathetic Nervous System activity during the experience of pain.
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Sebastião et al. (2022) conducted an observational in Healthy volunteers (Pain induction) (n=45). Cold Pressor Task (CPT) vs. Non-painful periods (Baseline, 37°C warm water, and rest) was evaluated on Physiological responses (Heart Rate, HRV, EMG, EDA) during pain induction. Pain induction via the Cold Pressor Task significantly increased heart rate, sudomotor activity, and muscle contraction force, while decreasing parasympathetic influence compared to non-painful periods.
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