Key result
Music-induced emotions are linked to a ~2% increase in QTc without altering intrinsic repolarization variability.
Why the study?
Emotions affect cardiac activity, but their impact on ventricular repolarization variability was unknown.
Does emotional valence induced by music affect ventricular repolarization variability in healthy volunteers?
Population
75 individuals without a history of cardiovascular disease
Comparison
Pleasant vs unpleasant music excerpts vs silent intervals
Design
Randomized crossover physiological study
Authors
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Music emotions may subtly shift QTc via HRV in healthy volunteers; leaves open arrhythmia relevance in patients.
Observational (n=75)
No
Does emotional valence induced by music affect ventricular repolarization variability in healthy volunteers?
Absolute Event Rate: 355% vs 347%
p-value: p=< 5x10^-7
Emotional valence affects ventricular repolarization dynamics primarily through changes in heart rate variability rather than intrinsic repolarization variability.
Orini et al. (2019) conducted an observational in Healthy volunteers (n=75). Music-induced emotional valence (pleasant and unpleasant music) vs. Silence (resting condition) was evaluated on Heart rate-corrected QT interval (QTc) (p=< 5x10^-7). Music-induced pleasant and unpleasant emotions caused a small but significant increase in QTc and a decrease in QT variability related to heart rate variability, without affecting intrinsic repolarization variability.
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