Why the study?
Does a prolonged H-V interval on His bundle electrogram affect acute mortality in patients with acute myocardial infarction complicated by AV or bundle branch block?
Does a prolonged H-V interval on His bundle electrogram affect acute mortality in patients with acute myocardial infarction complicated by AV or bundle branch block?
In patients with acute myocardial infarction complicated by conduction blocks, the presence of a prolonged H-V interval on His bundle electrogram does not significantly impact acute mortality, which is primarily driven by pump failure.
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Mortality in acute MI with conduction blocks is driven by infarct location; leaves open the prognostic role of His bundle electrograms.
Thirty-seven patients with acute myocardial infarction complicated by atrioventricular or bundle branch block, or a combination of both, has His bundle electrogram studies performed during their stay in the coronary care unit. The acute mortality of the 14 patients with a complicating bundle branch was 50%. Pump failure was the main cause of death. Three patients in this group had a prolonged H-V interval and one patient had a split blundle of His. The presence or absence of a prolonged H-V interval did not affect mortality in this group of patients. The acute mortality of the 16 patients with an inferior wall myocardial infarction was 6%. The H-V interval was normal in all but one of these patients. The atrioventricular block was caused by a proximal block in all cases. The acute mortality of the seven patients with an anterior wall myocardial infarction was 29%. The H-V interval was prolonged in two of seven patients. Pump failure was the acute cause of the deaths. The presence or absence of a prolonged H-V interval did not affect mortality in this group of patients.
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Gould et al. (1979) studied this question.
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