Carotici Artery Disease Following ExternalCervical Irradiation
Authors
Discussion
Loading...
Member takes
Implication
Cohort study demonstrates elevated carotid stenosis and stroke risk in long-term cervical irradiation survivors, indicating a need for routine noninvasive vascular screening.
Key Points
- To assess stroke incidence and detect occult carotid artery disease in patients surviving at least five years after external cervical irradiation.
- Retrospectively analyzed stroke incidence in 910 patients surviving at least five years after cervical irradiation for lymphoma or head and neck neoplasms over a mean follow-up of nine years.
- Prospectively screened 118 five-year survivors of cervical radiotherapy for occult carotid artery disease using carotid phonangiography (CPA) and oculoplethysmography (OPG).
- Stroke occurred in 63 of 910 patients (6.3%) during a mean nine-year observation period, reflecting an elevated trend (p = 0.39).
- Abnormal carotid phonangiograms were identified in 25% of patients and abnormal oculoplethysmographs were identified in 17% of patients, indicating unexpected, significant carotid lesions.
Cite This Study
Elerding et al. (1981) studied this question.