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January 1, 2000BloodOpen Access

The Jak-Stat pathway in normal and perturbed hematopoiesis

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Authors

AWAlister C. WardDeakin UniversityITIvo P. TouwErasmus MCAYAkihiko YoshimuraTokyo Institute of Technology

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Ward et al. (2000) studied this question.

synapsesocial.com/papers/6a1ef9ed52be8f5fb3e6b113https://doi.org/10.1182/blood.v95.1.19.001k34_19_29
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1TRANSCRIPTIONAL RESPONSES TO POLYPEPTIDE LIGANDS: The JAK-STAT Pathway1995 · 1,832 citations
  2. 2Dominant Negative Mutants Implicate STAT5 in Myeloid Cell Proliferation and Neutrophil Differentiation1999 · 106 citations
  3. 3GAS Elements: A Few Nucleotides with a Major Impact on Cytokine-Induced Gene Expression1997 · 450 citations
  4. 4Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway1999 · 367 citations
  5. 5Interferon-α Resistance in a Cutaneous T-Cell Lymphoma Cell Line Is Associated With Lack of STAT1 Expression1998 · 165 citations