Key result
Diabetes and hypertension linked to up to ~10% higher CVD risk, mediated by urbanicity.
Why the study?
Hypertension and diabetes increase cardiovascular disease risk, but the influencing and underlying factors remain unclear.
Does hypertension and diabetes increase the incidence of cardiovascular disease in adults in Cabo Verde?
Cross-Sectional (n=4,563)
Does hypertension and diabetes increase the incidence of cardiovascular disease in adults in Cabo Verde?
Hypertension and diabetes are significant risk factors for cardiovascular disease in Cabo Verde, with urbanization mediating and waist circumference moderating this relationship.
May inform urban-focused CVD risk assessment in Cabo Verde; hypothesis-generating and requires prospective confirmation before practice change.
BACKGROUND: Although hypertension and diabetes are known to increase cardiovascular disease risk, the influencing and underlying factors remain unclear. OBJECTIVE: To examine the mediating effect of location of residence and the moderating effects of recommended lifestyle practices in the hypertension/diabetes and cardiovascular disease nexus. MATERIAL AND METHODS: Data were drawn from 4,563 participants in Steps 1 and 2 of the 2020 World Health Organization's STEPS survey in Cabo Verde, with a subsample of 2,436 individuals completing Step 3. A logit regression model was employed to examine the correlations of cardiovascular disease, while structural equation modeling and interaction analysis were used to identify mediators and moderators within the explored relationships. RESULTS: < 0.001, respectively]. We identify urbanicity as a potential mediator through which hypertension/diabetes leads to a cardiovascular disease and waist circumference as a moderator of hypertension/diabetes-cardiovascular nexus. CONCLUSION: These findings add to the toolset of public health practitioners and policymakers in formulating policies and interventions aimed at managing cardiovascular diseases, particularly in developing nations.
No takes yet. Share an insight, caveat, or question.
Christian et al. (2024) conducted a cross-sectional in Cardiovascular disease risk factors (n=4,563). Hypertension and diabetes vs. Absence of hypertension or diabetes was evaluated on Incidence of cardiovascular disease (Marginal effect 0.0379 for hypertension and 0.1015 for diabetes, p=<0.001). Hypertension and diabetes were associated with a 3.79% and 10.15% increased probability of cardiovascular disease, respectively, with urbanicity acting as a mediator.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: