November 7, 2006Clinical Endocrinology
Association of metabolic syndrome with impaired heart rate recovery and low exercise capacity in young male adults
Key result
Metabolic syndrome in young adult males was associated with significantly lower heart rate recovery in the first minute (P<0.001) and mean exercise capacity (P=0.012) compared to obese controls.
Why the study?
Does metabolic syndrome impair heart rate recovery and exercise capacity in young adult males compared to obese or overweight controls?
Population
104 young adult males, including 64 newly diagnosed and untreated subjects with metabolic syndrome and 40…
Comparison
Metabolic syndrome vs Obese or overweight without metabolic syndrome
Design
Case-control
Authors
Discussion
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Implication
May identify young males at higher vascular risk; hypothesis-generating for autonomic screening in metabolic syndrome.
Study Design
Type
Observational (n=104)
Structured PICO
Does metabolic syndrome impair heart rate recovery and exercise capacity in young adult males compared to obese or overweight controls?
P
Population
104 young male adults (64 with newly diagnosed metabolic syndrome and 40 obese or overweight controls) evaluated for heart rate recovery during exercise stress testing.
E
Exposure
Metabolic syndrome
C
Comparator
Obese or overweight without metabolic syndrome
O
Outcome
Heart rate recovery (HRR) in the first, second, and third minutes of the recovery period after a symptom-limited exercise stress testsurrogate
Main Result
p-value: p=< 0.001
Young adult males with metabolic syndrome have impaired heart rate recovery and lower exercise capacity compared to obese controls without metabolic syndrome, suggesting a higher risk for future vascular events.
Cite This Study
Denız et al. (2006) conducted an observational in Metabolic syndrome (n=104). Metabolic syndrome vs. Obese or overweight controls without metabolic syndrome was evaluated on Heart rate recovery in the first minute of the recovery period and mean exercise capacity (p=< 0.001). Metabolic syndrome in young adult males was associated with significantly lower heart rate recovery in the first minute (P<0.001) and mean exercise capacity (P=0.012) compared to obese controls.