Population
46 consecutive Caucasian patients with idiopathic recurrent acute pericarditis (IRAP)
Design
Cohort
Key result
Among patients with idiopathic recurrent acute pericarditis, 8.7% developed primary Sjögren's syndrome and 2.2% rheumatoid arthritis, with no FMF mutations found, supporting an autoimmune etiology.
Authors
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May warrant autoimmune evaluation in idiopathic recurrent pericarditis; leaves open whether screening improves outcomes.
Cohort (n=46)
The development of definite immunorheumatological diseases and the absence of FMF mutations support the hypothesis that idiopathic acute recurrent pericarditis is an autoimmune condition.
Brucato et al. (2005) conducted a cohort in Idiopathic recurrent acute pericarditis (n=46). Idiopathic recurrent acute pericarditis was evaluated on Occurrence of new diagnoses of autoimmune diseases, HLA typing, and presence of FMF mutations. Among patients with idiopathic recurrent acute pericarditis, 8.7% developed primary Sjögren's syndrome and 2.2% rheumatoid arthritis, with no FMF mutations found, supporting an autoimmune etiology.