Key result
Breast cancer survivors (n=5,421) and non-cancer controls (n=21,684) aged ≥65 years had a similar prevalence of depressive symptoms, which were strongly associated with multiple comorbidities.
Why the study?
The study was conducted to examine the prevalence of depressive symptoms and associated risk factors in older adult breast cancer survivors compared to age-matched non-cancer controls.
Are depressive symptoms more prevalent in older adult breast cancer survivors compared to age-matched non-cancer controls?
Observational (n=27,105)
Are depressive symptoms more prevalent in older adult breast cancer survivors compared to age-matched non-cancer controls?
Older adult breast cancer survivors do not have a higher prevalence of depressive symptoms than non-cancer controls, but multiple comorbidities and functional limitations are key risk factors for both.
Similar depressive symptom rates in older survivors and controls link to comorbidities; leaves open comorbidity-focused screening over cancer history alone.
OBJECTIVES: To examine the prevalence of depressive symptoms and associated risk factors in older adult breast cancer survivors (BCS) and age-matched non-cancer controls. SAMPLE & SETTING: Using the Surveillance, Epidemiology, and End Results-Medicare Health Outcome Survey linked dataset from 1998 to 2012, BCS and non-cancer controls aged 65 years or older were identified. METHODS & VARIABLES: Depressive symptoms, comorbidities, functional limitations, socio-demographics, and health-related information were examined. Univariate and multivariable logistic regression and marginal models were performed. RESULTS: 5,421 BCS and 21,684 controls were identified. BCS and non-cancer controls had similar prevalence of depressive symptoms. Having two or more comorbidities and functional limitations were strongly associated with elevated risk of depressive symptoms in BCS and non-cancer controls. IMPLICATIONS FOR NURSING: Having multiple comorbidities and multiple functional status are key factors associated with depressive symptoms in older adult BCS and non-cancer controls. Nurses are in an ideal position to screen older adult BCS and non-cancer controls at risk for depressive symptoms.
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Paek et al. (2021) conducted an observational in Breast cancer and depressive symptoms (n=27,105). Breast cancer survivorship vs. Age-matched non-cancer controls was evaluated on Prevalence of depressive symptoms. Breast cancer survivors (n=5,421) and non-cancer controls (n=21,684) aged ≥65 years had a similar prevalence of depressive symptoms, which were strongly associated with multiple comorbidities.
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