Why the study?
Does atenolol prevent the decline in stroke volume during prolonged exercise in active men?
Population
7 active men cycling for 60 min at approximately 57% peak O2 uptake in a neutral environment
Comparison
Atenolol approximately 7 mg oral dose at the… vs Placebo control (CON) at the onset of exercise
Design
Other
Follow-up
60 min
Authors
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Confirms rising heart rate drives stroke volume decline in prolonged exercise; hypothesis-generating for beta-blockade effects in endurance settings.
Does atenolol prevent the decline in stroke volume during prolonged exercise in active men?
During prolonged exercise in a neutral environment, the decline in stroke volume is driven by the increase in heart rate rather than changes in cutaneous blood flow.
Fritzsche et al. (1999) studied this question.
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