Why the study?
Does treatment of hyperthyroidism resolve thymic hyperplasia presenting as a mediastinal mass in a patient with Hodgkin disease?
Does treatment of hyperthyroidism resolve thymic hyperplasia presenting as a mediastinal mass in a patient with Hodgkin disease?
Thymic hyperplasia can present as a residual mediastinal mass in patients with Hodgkin disease and hyperthyroidism, and may resolve with treatment of the hyperthyroidism.
Hyperthyroidism treatment may resolve thymic hyperplasia as mediastinal mass in Hodgkin disease; hypothesis-generating, needs prospective validation.
A 19-year-old woman had a residual gallium-sequestering mediastinal mass after treatment for Hodgkin disease. Coincidentally, she also had hyperthyroidism. The initial concern was that the mass was residual Hodgkin disease. Thymic hyperplasia has been described in association with both these conditions. The mass disappeared after treatment of her hyperthyroidism.
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Pendlebuy et al. (1992) studied this question.
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