⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

March 23, 1987FEBS Letters

Mode of inhibition of sodium azide on H⁺‐ATPase of Escherichia coli

Takato Noumi Masatomo Maeda Masamitsu Futai

View at Publisher

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

Sodium azide inhibited multi-site (steady-state) ATPase activity of E. coli F1 more than 90%, but did not affect uni-site (single-site) ATPase activity. Thus azide inhibited multi-site ATPase activity by lowering catalytic cooperativity. Consistent with this observation, azide changed the ligand-induced fluorescence response of aurovertin bound to F1.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Noumi et al. (1987) studied this question.

synapsesocial.com/papers/6a1f2ce1ad2f36b9a8915d20 https://doi.org/10.1016/0014-5793(87)81526-0

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

1Structure and function of proton-translocating adenosine triphosphatase (F0F1): biochemical and molecular biological approachesOriginal Research · 1983 · 373 citations
2The Proton-Translocating Pumps of Oxidative PhosphorylationOriginal Research · 1980 · 257 citations
3Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate constants for elementary steps in catalysis at a single site.Original Research · 1982 · 406 citations
4Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate enhancements resulting from cooperative interactions between multiple catalytic sites.Original Research · 1982 · 344 citations
5The defective proton-ATPase of uncD mutants of Escherichia coli. Two mutations which affect the catalytic mechanism.Original Research · 1985 · 94 citations
6Replacement of arginine 246 by histidine in the beta subunit of Escherichia coli H+-ATPase resulted in loss of multi-site ATPase activity.Original Research · 1986 · 99 citations
7Fluorescence Change Of Auramine O Bound to Chromatophores of Rhodospirillum rubrum — Analysis in Connection to Ionic Environment and Ion TransportOriginal Research · 1972 · 71 citations
8Change of Inhibitor Sensitivities of Escherichia coli F1-ATPase Due to a Mutational Substitution of Phe for Ser at Residue 174 of the β Subunit1Original Research · 1985 · 20 citations
9How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactomeFEBS Letters · 2026
10Synthetic nanobodies for drug discovery—Design, construction, optimization, and applicationsFEBS Letters · 2026

More from FEBS Letters

More from The University of Osaka