Case report reveals fatal cardiopulmonary arrest from non-toxigenic Corynebacterium diphtheriae in a young adult, suggesting systemic infection can trigger severe cardiogenic toxicity.
Here we document a rare, acute, infection caused by non-toxigenic Corynebacterium diphtheriae and the resulting unique and severe clinical sequelae. Our patient was a young man with no known pre-existing conditions that presented in cardiopulmonary arrest. We contrast this case with prior instances of non-toxigenic C. diphtheriae strain infection in the United States and summarize the literature that suggests systemic infection can result in cardiogenic toxicity. We speculate on a possible missed, pre-existing condition that could have increased this patient’s susceptibility to poor clinical outcome.
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Alvarez et al. (2023) studied this question.
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