Key result
Life Goals Collaborative Care reduced systolic (β = -3.1, P=.04) and diastolic blood pressure (β = -2.1, P=.04) compared to enhanced usual care in patients with bipolar disorder.
Why the study?
Does Life Goals Collaborative Care reduce cardiovascular risk factors and improve physical and mental health outcomes in patients with bipolar disorder and ≥ 1 CVD risk factor?
Population
118 US Department of Veterans Affairs patients with an ICD-9 diagnosis of bipolar disorder and ≥ 1 CVD risk…
Comparison
Life Goals Collaborative Care including 4 weekly… vs Enhanced usual care including quarterly wellness…
Design
RCT, randomized to LGCC or enhanced usual care
Follow-up
24 months
Authors
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Supports collaborative care for BP reduction in bipolar disorder with CVD risk; extends evidence for multidisciplinary models to cardiometabolic outcomes.
RCT (n=118)
Does Life Goals Collaborative Care reduce cardiovascular risk factors and improve physical and mental health outcomes in patients with bipolar disorder and ≥ 1 CVD risk factor?
Effect estimate: β = -3.1 for systolic BP, β = -2.1 for diastolic BP
p-value: p=0.04
A collaborative care intervention significantly reduced systolic and diastolic blood pressure in patients with bipolar disorder and cardiovascular risk factors.
Kilbourne et al. (2013) conducted an RCT in Bipolar disorder with ≥ 1 CVD risk factor (n=118). Life Goals Collaborative Care (LGCC) vs. Enhanced usual care was evaluated on Systolic and diastolic blood pressure, nonfasting total cholesterol, and physical health-related quality of life (β = -3.1 for systolic BP, β = -2.1 for diastolic BP, p=0.04). Life Goals Collaborative Care reduced systolic (β = -3.1, P=.04) and diastolic blood pressure (β = -2.1, P=.04) compared to enhanced usual care in patients with bipolar disorder.
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