Key result
Noninvasive indices of baroreceptor sensitivity correlated with the phenylephrine method (r=0.70) but had wide limits of agreement, indicating they should not be used as clinical alternatives.
Why the study?
Do noninvasive indices of baroreceptor sensitivity agree with the phenylephrine method in post-myocardial infarction patients?
Population
52 consecutive patients with recent myocardial infarction
Comparison
Noninvasive baroreflex sensitivity tests during… vs Phenylephrine method for baroreflex sensitivity
Design
Cross-sectional
Authors
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Wide limits of agreement caution against interchangeable use post-MI; leaves open prospective validation of refined noninvasive methods.
Observational (n=52)
Do noninvasive indices of baroreceptor sensitivity agree with the phenylephrine method in post-myocardial infarction patients?
Effect estimate: r=0.70
Noninvasive baroreflex sensitivity assessments have wide limits of agreement with the phenylephrine method and should not be used as clinical alternatives in post-MI patients.
Pitzalis et al. (1998) conducted an observational in Recent myocardial infarction (n=52). Noninvasive indices of baroreceptor sensitivity (alpha-index and sequence analysis) vs. Phenylephrine method was evaluated on Correlation and agreement between baroreflex sensitivity obtained with phenylephrine and noninvasive methods (r=0.70). Noninvasive indices of baroreceptor sensitivity correlated with the phenylephrine method (r=0.70) but had wide limits of agreement, indicating they should not be used as clinical alternatives.
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