August 1, 1996Hypertension
Noninvasive Assessment of Baroreflex Control in Borderline Hypertension
Why the study?
Do noninvasive baroreflex measurement techniques accurately assess baroreflex sensitivity compared to the phenylephrine method in normotensive and borderline hypertensive subjects?
Population
42 subjects, comprising normotensive subjects (n=27) and borderline hypertensive subjects (n=15).
Comparison
Noninvasive baroreflex measurement techniques vs Invasive pharmacological method
Design
Cross-sectional
Authors
Discussion
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Implication
Noninvasive estimates correlate with phenylephrine baroreflex sensitivity; hypothesis-generating for clinical alternatives in hypertension.
Structured PICO
Do noninvasive baroreflex measurement techniques accurately assess baroreflex sensitivity compared to the phenylephrine method in normotensive and borderline hypertensive subjects?
P
Population
42 subjects, comprising normotensive subjects (n=27) and borderline hypertensive subjects (n=15).
I
Intervention
Noninvasive baroreflex measurement techniques (spectral analysis and sequence detection of covariations of systolic pressure and RR interval)
C
Comparator
Invasive pharmacological method (phenylephrine-induced increases in systolic pressure and RR interval)
O
Outcome
Baroreflex sensitivitysurrogate
Noninvasive methods like spectral analysis and sequence detection provide viable alternatives to pharmacological approaches for estimating baroreflex sensitivity in hypertension.
Cite This Study
Watkins et al. (1996) studied this question.