Key result
Spontaneous baroreflex sequences and spectral analysis showed acceptable agreement with pharmacological methods, with all methods detecting lower baroreflex sensitivity in hypertensives (P<0.05).
Why the study?
Do newer techniques based on spontaneous sequences and spectral analysis agree with established pharmacological methods for assessing arterial baroreflex sensitivity in elderly subjects?
Population
20 elderly subjects, comprising 10 hypertensive and 10 normotensive individuals
Comparison
Assessment of arterial baroreflex sensitivity… vs Assessment of arterial baroreflex sensitivity…
Design
Cross-sectional
Authors
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Noninvasive baroreflex methods may aid elderly hypertensive assessment; leaves open prospective outcome validation before wider use.
Cross-Sectional (n=20)
Do newer techniques based on spontaneous sequences and spectral analysis agree with established pharmacological methods for assessing arterial baroreflex sensitivity in elderly subjects?
p-value: p=<0.05
Newer non-invasive techniques for assessing arterial baroreflex sensitivity show acceptable agreement with traditional pharmacological methods in elderly patients, offering a more physiological assessment at rest.
James et al. (1998) conducted a cross-sectional in Hypertension (n=20). Spontaneous baroreflex sequences and spectral analysis vs. Pharmacological methods (sodium nitroprusside and phenylephrine) was evaluated on Baroreflex sensitivity (p=<0.05). Spontaneous baroreflex sequences and spectral analysis showed acceptable agreement with pharmacological methods, with all methods detecting lower baroreflex sensitivity in hypertensives (P<0.05).
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