Key result
Noninvasive methods of measuring baroreflex sensitivity correlated significantly with the phenylephrine technique (R=0.39-0.55, P≤0.001) but underestimated it and could not be used interchangeably.
Why the study?
Do noninvasive measures of baroreflex sensitivity correlate with the established phenylephrine bolus method in aging and hypertensive patients?
Population
149 young and middle-aged normotensive and hypertensive patients
Comparison
Noninvasive measures of baroreflex sensitivity vs Phenylephrine bolus injection
Design
Cross-sectional
Authors
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Noninvasive baroreflex measures should not replace phenylephrine testing in practice; leaves open their research utility for detecting hypertension-related impairment.
Cross-Sectional (n=149)
Do noninvasive measures of baroreflex sensitivity correlate with the established phenylephrine bolus method in aging and hypertensive patients?
Effect estimate: R = 0.39 to 0.55
p-value: p=≤0.001
Noninvasive methods of measuring baroreflex sensitivity correlate with the phenylephrine bolus technique but cannot be used interchangeably, though spectral domain analysis effectively detects hypertension-related baroreflex loss.
Milic et al. (2009) conducted a cross-sectional in Hypertension (n=149). Noninvasive measures of baroreflex sensitivity vs. Phenylephrine bolus injection was evaluated on Correlation between phenylephrine method and noninvasive measures of BRS (R = 0.39 to 0.55, p=≤0.001). Noninvasive methods of measuring baroreflex sensitivity correlated significantly with the phenylephrine technique (R=0.39-0.55, P≤0.001) but underestimated it and could not be used interchangeably.
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