Key result
Percutaneous transluminal coronary angioplasty resulted in lower angina-free rates at 5 years compared to bypass surgery (79% vs 85%, P=0.007), though differences narrowed over time.
Why the study?
Does PTCA compared to CABG improve clinical and functional status in patients with multivessel coronary disease?
Population
1829 patients with multivessel coronary artery disease suitable for both CABG and PTCA and not previously…
Comparison
Percutaneous transluminal coronary angioplasty… vs Coronary artery bypass grafting within 2 weeks…
Design
RCT, randomized
Follow-up
average 5.4 years
Loading...
PTCA yields less sustained angina relief than CABG in multivessel disease; extends RCT evidence favoring surgery for symptom control.
RCT (n=1,829)
Randomized
Yes
Does PTCA compared to CABG improve clinical and functional status in patients with multivessel coronary disease?
Absolute Event Rate: 79% vs 85%
p-value: p=0.007
In patients with multivessel coronary disease, initial differences in angina relief favoring CABG over PTCA narrow by 5 years, though PTCA patients require more anti-ischemic medications and repeat revascularizations.
A 1997 study conducted an RCT in Multivessel coronary artery disease (n=1,829). Percutaneous transluminal coronary angioplasty (PTCA) vs. Coronary artery bypass grafting (CABG) was evaluated on Angina-free rates at 5 years (p=0.007). Percutaneous transluminal coronary angioplasty resulted in lower angina-free rates at 5 years compared to bypass surgery (79% vs 85%, P=0.007), though differences narrowed over time.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: