Key result
Medial open reduction for developmental dysplasia of the hip was associated with a 20% rate of clinically significant avascular necrosis, leading to more unsatisfactory outcomes (55% vs 20%; P<0.001).
Why the study?
What is the incidence of avascular necrosis following medial open reduction in children with developmental dysplasia of the hip?
Systematic Review (n=734)
What is the incidence of avascular necrosis following medial open reduction in children with developmental dysplasia of the hip?
Medial open reduction for DDH carries a 20% risk of clinically significant AVN, which is increased by surgery before 12 months of age and post-operative abduction ≥60°.
Medial open reduction for DDH warrants cautious use given AVN-driven failures; confirms AVN as a dominant driver of unsatisfactory outcomes and informs technique optimization.
The incidence of clinically significant avascular necrosis (AVN) following medial open reduction of the dislocated hip in children with developmental dysplasia of the hip (DDH) remains unknown. We performed a systematic review of the literature to identify all clinical studies reporting the results of medial open reduction surgery. A total of 14 papers reporting 734 hips met the inclusion criteria. The mean follow-up was 10.9 years (2 to 28). The rate of clinically significant AVN (types 2 to 4) was 20% (149/734). From these papers 221 hips in 174 children had sufficient information to permit more detailed analysis. The rate of AVN increased with the length of follow-up to 24% at skeletal maturity, with type 2 AVN predominating in hips after five years' follow-up. The presence of AVN resulted in a higher incidence of an unsatisfactory outcome at skeletal maturity (55% vs 20% in hips with no AVN; p < 0.001). A higher rate of AVN was identified when surgery was performed in children aged < 12 months, and when hips were immobilised in ≥ 60° of abduction post-operatively. Multivariate analysis showed that younger age at operation, need for further surgery and post-operative hip abduction of ≥ 60° increased the risk of the development of clinically significant AVN.
No takes yet. Share an insight, caveat, or question.
Gardner et al. (2014) conducted a systematic review in developmental dysplasia of the hip (DDH) (n=734). Medial open reduction was evaluated on Clinically significant avascular necrosis (AVN) (types 2 to 4). Medial open reduction for developmental dysplasia of the hip was associated with a 20% rate of clinically significant avascular necrosis, leading to more unsatisfactory outcomes (55% vs 20%; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: